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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '111c3b741310d54c48de2b23a072168b2422ab3db6c44955a91b7c278c696c1f' 
  AND token = 'n09ChICHqnw7zRcSVEE5WxQF4ISrISBk7/quRLDwhoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}