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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6481c1c126893c5a44fd4775fcccf7b405cce5b4373433c96e60a97cd7339c3' 
  AND token = 'deJubHPtUreo75kM/VzhLlWG7boNrkEfZYeJiAwkW90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}