SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4ae15a7fd40fdfc35a3c776145937b6b34cc37288ab9377c38b4d719687611f' 
  AND token = 'fK9+5L02WCrDGV3UI1sCfClmBGFBZMLAoFQKpcLpNWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}