SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a2a9b516fc36029a50d57ebb224e5cbdd60a56c0eb9636004fcd64d55eebde8' 
  AND token = 'TSyqx4L9R+3e3vrZvJm1FpINZszZLn11PFuaJ8aCcKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}