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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67d20e54c704c53bfaae4da23be8c4b0ea9714e4998db9857fd76bb257dc3d3e' 
  AND token = 'xpGaO48L+wMixbHz4yoiOcMt4svkwQog1rDzC0taPwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}