SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d5e8d28829d48cb6a7ee975d68800345c80709dadbde9c80a8c57c3d00784fd' 
  AND token = 'wWRukRfT8WpITRvRwkMKY2CDQ1ZSxy2304rIMjPWSIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}