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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '211f0b862a9924a5a68824e232daedfee5d6e636925647382e5c257b4ffa2d31' 
  AND token = '0RusG28Dkp0NU5/99Mi/i77/bqRv2J9WDfL2ry2sN6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}