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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a44accef2fc84f65de2bbbc13c61b8e205b50b23d9512dfa2e96a90f4ecd008' 
  AND token = 'YHcL2UccORmjcTcwQSjvw4XjvcynejAmbLkgczDLU8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}