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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e65530645fae4832f7906d0cba525586ca5676f69baf81e153f416576e7c785f' 
  AND token = 'rbvEOwokzok7nzd1UOOnClt5RbjysqMB/whfofgKjXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}