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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66a8bbb7fa614c814a7ea3ce1a1a1b7db9a91c1d46edaed47187ca10109f3a9d' 
  AND token = 'QNvAMMt5/UL6OGGiKRHMgZU3vytcKHk/ojcuF2dB8nM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}