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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e481be29421fb89661bb74621f9932e9b1472820591e3c2ca3e179b0d2b2a2f8' 
  AND token = '5WLVAEBCBSId+dftn0prjgxNS7vEEVP/XCpCten5KXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}