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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3eda4f48128e9690874a0d31a72bed71cdaa5a0a1bcbbf8ddf3a4a980e05927' 
  AND token = 'COw7EwQltx/8T0tXUY9gl5DFi8qd47/0CoXucO+5+HM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}