SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db22e0dbd0f26cba9eee210e24fd00db9d1a3355e7f386603fc6607c715ef4e3' 
  AND token = 'PN1EB4j8WR+xm1kenWe2ZZcFv27eGckCZ/omDH17VHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}