SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f0b1ed189f5f800c5de70ad63dc653c49561f845941dd9a0508834b96564fe9' 
  AND token = 'LMShtyATlWOOG/VBQs+KyNMOacOhd6DmAX/QE8SjnUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}