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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53163adf649ca5701d7a8a07b5fdb28a47b22e43b3f9cff1589a6e2e275da5f6' 
  AND token = 'PekbRFX51oRX71e4Q+7kWZbVn2kaTr8d4bJMgnGRiZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}