SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2619df33279ceb3dce98734b1a7d2b136a1c976270b2a55a8350d4d832ed2511' 
  AND token = 'fbjxRSHoiRKeZ3J/SNDFAIpo8TXs9o+qxXoFEIbtQGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}