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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b50e8e3c7aeb5a5cafb80214d1f9991bc703ff445a580d6f1fdde795d8444da' 
  AND token = 's8jndXRhC0qhkj3HYJG25UAyu2mhBTJOXH8PMDVl9Oc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}