SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a0ccdcacc92ea41e236b704f981a7ea553c35c1177babe3cafbe98a1a836e28' 
  AND token = 'RDYr/2u4+rQhB4fW19+cQLW8RefFZEgqG9fv6gqZQZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}