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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae64fa2461ace262cd8ef9a4dc3371015c16ae188ad1598b2f8f2bf4745bd4c4' 
  AND token = 'Amucu72sOPRt0sSY4xc/40GwqU+FZr0wgGY2/7pCn0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}