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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b146392980f8c19d7dd6f9b21230236fbb4bf47a6650b1e38e87d68e07cc1c3' 
  AND token = 'EMlcZCa3CcWJFvM2LXsskQLDoDmAR3RwumOY5io5pSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}