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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '243015f0f572cd46163a29fb90958cd2f2d0426c7c423e009071cba090c54413' 
  AND token = 'n0ufd4wxl6TdDwZbXPcV2CtHTl2awGIZ8ILpw7nNWBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}