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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b92ccdf483e6578b00d55913a82f187b41b1a0a03d7d628cadddfff1a26dd4a5' 
  AND token = 'z+gDNNIheGrM77qx1xKgYB77DEnUS8mA0Jqoxn1UxnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}