SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '450bec8cb78cda23b260b9de44c5fcd91398e1539dc0f43e0fa7fa29aaafce54' 
  AND token = 'Hho6WVahOtiQPahUbTRQT8pCHW+lAOBsf03hH7V7KT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}