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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '500b684b19f78fc4c7d00394b133d43f344f3fe12c444e6ba9f3b0d83d0ad08e' 
  AND token = '9qndZLRcW/Nu/cmMw82miTx/H2ij/mGV1nXM6MmhZ0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}