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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8bb5f76c186a6fca612189fca2bc505d8d159e244355d1c3b90a6a0531bad6c' 
  AND token = 'FvET3cxlKUsKF9yC8in6JHF4YeIgR60P5o8DJV0gt9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}