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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f9e5e0c1a9fd3bf7235df79be18df7f6bc1ece9f3a4b36707bedabc06111d51' 
  AND token = '21Qk44XJ9xyy6MnF+1eehYKkR9pAuirW4CGveL1rNcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}