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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f992ae75b26a1de8a6c18c8b50d59e1c2293430206d49d8edfed42484a9082e8' 
  AND token = 'fyn8aqlNi1wzFc+Lv1Oa9j4Mv2M18RUXOHr1Xi1piJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}