SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4da07bbee5ec21ba29885d6f22d485448e8e8842ad51f6291cd544cad8f9c01' 
  AND token = 'CM5SU0b+x1vlCJ9v7+mT71OUWBwUru24lzbWeJ7q+Hw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}