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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5cf6381ed53e9a5983736b66e606b8d3dd9392f8bbbfebdd8fb570da61ba95c' 
  AND token = '6i3HqN54llk+X60kNFUxoD0fkYNoGgbsOW/iWz0Vwqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}