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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be5408d1e039cf199c4e61486ea2b81f81457d3fcac8cb140841246042a2c540' 
  AND token = 'DH+tQ1YW9UFCC+o5cmFQhC6a2+4wuUF1DRiRq2fOmnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}