SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc401ddb085744e22e0d205623fec7a2afde1e4343363ea601a8268c364eaf06' 
  AND token = 'apZ/xVmNDTwFA48nv0p/jffTAD09kx/oOW+K5EgOHVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}