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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c7d2436b662793a8664151d3c468b37ec42a5cd16f30c9229ddea8f2383c161' 
  AND token = 'q4oEIcLuV8SZtXNfH5S5eqZrAmfATJ3Vq4ww/hek6bw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}