SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80e349f3e6060a7eb27d8da12975574ff8d738470004727f8bbbd835e43254e9' 
  AND token = '9VNEctHTcfQmnYNLU871eM7sYNWEZ1vsDvQFx1n9i6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}