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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0845eaef31831487b00ca44d91c1137a4c4efd365e14f7f4b53d936da495304' 
  AND token = '/t48ClxzAKcO0VJ3Ces+shgEeQH2+FsLBQ+pkn9yTWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}