SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46055a6f66b4d6be773f9baf5a97b8133e4a1b2b7666861b170996a7a6b11e68' 
  AND token = 'wQZoLhmhA6sV19d7Pe8tavULm+Yp9Jsxd7ewl2Q+Q90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}