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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3197d5d20ea1528d07282e6dcf20b42f6d1774d0708686772e4a51c397c6b607' 
  AND token = 'QpU/Q6zuov6Ys+lL8Nm8yU+jY7Pys0Dc+rFHT6M10ZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}