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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2e487fe160437c09f955642d97e419271977d582e1dcbcc2d2b6278b7d981ee' 
  AND token = 'k1OODzuXJVv4pRH37ciLO/K3E7gc7z7s1n54xcdYfOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}