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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f10e26ab544b3007f00a9d31474f01117e2cc9b67348fbb3df8b12c7ff21857' 
  AND token = 'fT0wOOsXEClwO6DzjvQNkiXswd/tFq1FtpHSHSyhQzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}