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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb043f4eeb1baac3c309d65485d0decc745c787b166a6d0e057e697b77290a6d' 
  AND token = 'XXINSic5VTp/B6PybQqUhzPX5L0vt01wXkdBiYDEwl4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}