SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cc6b7a026b1a978829a4f7dafb45a2f31bbe1142c3ce13a7d64b0e55e67fb1d' 
  AND token = 'mLsAD0BY44AM1uxokwKjq65hIrBXbOstZ8WyhefOgQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}