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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f88013545de0c73c0bedeced7129ff260b1c33649f61173b5f0b84cae8b2e606' 
  AND token = 'wipuFQr9ZlHeCyxwzt3CJQVGD4PfAijTX7euxwg7gTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}