SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9edb46d61aaa3c59334a56e116a5fb69099ce9ff7a4beccc8435ffe516dc1969' 
  AND token = 'oD2a6nYO2i3lfJYqSFmcXJhY1KQzYZSKFYblqSWTVeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}