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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bfc5700a878fa82b1a1513132f88f0c4375698d4ff963ed48378c73c3258c39' 
  AND token = 'zMMPe6Xd8HCeBErf7XHMWrcNlwKq3NoJzBd+RAkRQgo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}