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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fab29b218a4b21ebdb510ffea43fb97e44f294c62e4625f3d1540e78eb7c570' 
  AND token = 'vwYnv4bGU1u/mwHp37Fp0Ao5Ryb8PehoyEmFYM606EM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}