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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a2876f719fec65fe6b1ac4dc381e8f8cb6de7f1b1b1e1f6729d48a901dbe6c5' 
  AND token = 'Qu1gP7V1iOToD4sIRFLwG1AyRBbBsKfEM4xU4G2YF6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}