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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ae54b2a622db4f14daafdc175e6be2f17af5a3129dd0d352f5ccced814bd2bb' 
  AND token = 'nDetQg4jdGGtbVdJwom92CA3AOe0cTBFyMM229W/nkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}