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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a691fe67b785dbd03b148d4d1d9658dc72eaf77de3acd9232ec415e99af5bab2' 
  AND token = 'yFPM4mUyWPUkHFt2++y+rHWJpmzTzxoy0cPk3C/gr7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}