SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a259f5e8d3f3ad1f65e749f1801bd99734131249281ef07d1d501dc31d15ea8b' 
  AND token = 'xa5v6qR/B8QwUhPDMB8ig6uZVAU7Nqb26nW2WFOn34c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}