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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '902ee49c9a1aebda442cc66976007113a91c2a276f5cb1f8d4138beed5b8e4a2' 
  AND token = 'eVRgjk9DXhb6ABcvCUo1KqKtUEkmbsX3/Wi1Jpve8b0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}