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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80a93f1e177146685ba4616a0be699c7d2365ec7e48a0ad4989f49b4008e29ca' 
  AND token = 'aaui0XH/dckSG5nXb06JM6nXxEl2jXkuerrbdehXOGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}